Avoid using drugs that make you sleepy (such as cold medicine, other pain medications, muscle relaxants, and medicine for seizures, depression or anxiety). These drugs may slow your breathing or increase drowsiness when used together with tramadol.Tramadol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
a red, blistering, peeling skin rash; or
shallow breathing, weak pulse.
Continue taking tramadol and talk to your doctor if you have any of these less serious side effects:
dizziness, drowsiness, weakness;
nausea, vomiting, constipation, loss of appetite;
flushing (redness, warmth, or tingly feeling); or
sleep problems (insomnia).
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
You may be more likely to have a seizure (convulsions) if you take tramadol while you are using certain other medicines. Do not take tramadol without telling your doctor if you also use any of the following:
an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam); or
an antidepressant such as amitriptyline (Elavil), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor); paroxetine (Paxil), or sertraline (Zoloft).
Before taking tramadol, tell your doctor if you also use:
digoxin (Lanoxin, Lanoxicaps);
erythromycin (E-Mycin, E.E.S., Ery-Tab);
rifampin (Rifadin, Rimactane, Rifater);
St. Johns wort;
quinidine (Quinaglute, Quinadex, Cardioquin, Quinora); or
drugs that make you sleepy (such as cold medicine, other pain medications, muscle relaxants, and medicine for seizures, depression or anxiety).
If you are using any of these drugs, you may not be able to use tramadol or you may need dosage adjustments or special tests during treatment.
There may be other drugs not listed that can affect tramadol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Tramadol is available with a prescription under the brand names Ultram and Ultram ER. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.
Tramadol 50 mg--white, capsule-shaped, film-coated tablets.
Ultram ER 100 mg, 200 mg, 300 mg--white, round extended-release tablets.